Hair Loss/Prostate Drugs Can Have Unwanted Sexual Side Effect

Two drugs that are used to treat hair loss and enlarged prostate may cause an unwanted side effect in some men: erectile dysfunction.

Researchers at Northwestern University Feinberg School of Medicine examined the medical records of nearly 12,000 men who had taken either Avodart (dutasteride) or Propecia/Proscar (finasteride). Higher doses are used to treat an enlarged prostate that results in more frequent urination, while smaller doses are used for hair loss.

About 1.4% of the men developed long-term erectile dysfunction (ED) after taking one of the drugs, researchers reported in the journal PeerJ. While that’s a relatively small percentage, those who did experience ED had it last an average of 3.5 years after they stopped taking the drug.

Results also showed that young men (aged 16-42) who took Propecia or Proscar for at least 205 days had a nearly 5 times higher risk of persistent ED than men with shorter exposure. And men without prostate disease who used an NSAID painkiller (such as Advil or Aleve) with at least 209 days of use of one of the 2 drugs had a 4.8-fold higher risk of persistent ED than men with shorter exposure.

Overall, the longer a man took one of the drugs, the more likely he was to develop an ED problem.

Propecia was in the news recently when it was revealed President Trump takes Propecia for hair loss. Questions about sexual – and other – side effects have plagued Propeciasince its approval, as there have also been cases of suicidal thoughts and depression associated with the drug.


Jonathan Block

Jonathan Block

Jonathan Block is an associate editor at BioCentury, which provides news and information about the biotechnology and pharmaceutical industries. Prior to joining BioCentury in 2019, Jonathan worked for MedShadow as content editor. He has been an editor and writer for multiple pharmaceutical, health and medical publications, including The Pink Sheet, Modern Healthcare, Health Plan Week and Psychiatry Advisor. He holds a BA from Tufts University and is earning an MPH with a focus on health policy from the CUNY Graduate School of Public Health & Health Policy.


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